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References
Awards
cONTRIBUTIONS
British plant biologist known for her research on the molecular mechanisms that control flowering time in plants (2).
Week 13: Memory
Caroline Dean
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SCIENTIST SPOTLIGHT
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Transcript

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SCIENTIST SPOTLIGHT

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ABout

ABOUT

  • She is 66 years old
  • Has a PhD in Biology from University of New York (2)
  • She is a group leader at the John Innes Centre in Norwich, UK (2) Via twitter @CarolineDeanLab
  • She has two children
  • Married to Jonathan Jones, a scientist who specializes in genetic approaches for studying disease resistance in plants (2)

Caroline Dean

Week 13: Memory

British plant biologist known for her research on the molecular mechanisms that control flowering time in plants (2).

cONTRIBUTIONS

CONTRIBUTIONS Caroline Dean has made significant contributions to the field of plant biology, particularly in the area of flowering time regulation and epigenetics. Some of her major contributions include:

  • The discovery of the FLC gene which plays a critical role in regulating the timing of flowering in Screenshot from YT (3) response to changes in temperature and other environmental cues (2).
  • This discovery has lead to scientists to understand epigenetic memory in plants.
  • Dean's research showed that FLC expression is regulated by epigenetic modifications.
  • These modifications act as a type of "memory" that allows plants to remember changes in temperature over time and adjust their flowering accordingly. This is the vernalization pathway, a molecular pathway that controls flowering time in response to prolonged cold exposure (3) .
  • In other words, repressing FLC expression is an important step in the vernalization process, which enables plants to flower after exposure to prolonged periods of cold temperatures. When FLC is expressed at high levels, it prevents other genes involved in flowering from being expressed.

Awards

AWARDS

  • In 2004 Dean was appointed office of the Dame Commander of the Order of the British Empire (DBE) and a Fellow of the Royal Society (4)
  • In 2016 Dean was awarded with the Darwin Medal by the Royal Society (4)
  • In 2020 awarded the Royal Society 'Royal MedalFUNZIES
  • Scientist and influencer Twitter handle @CarolineDeanLab (5)
  • Entertainer too
  • "Play is the best way to learn and understand. Therefore, members of the lab developed this amazing FLC UNO game"

References

References

  1. Gitschier J (2013) How Cool Is That: An Interview with Caroline Dean. PLoS Genet 9(6): e1003593. doi:10.1371/journal.pgen.1003593
  2. “Professor Dame Caroline Dean.” John Innes Centre, 22 July 2021, https://www.jic.ac.uk/people/caroline-dean/.
  3. John Innes Centre. “How Do Plants Remember - Professor Caroline Dean.” YouTube, 16 June 2016, https://youtu.be/mLGGZwSYOP4.
  4. “Caroline Dean.” The Royal Society, 2016, https://royalsociety.org/people/caroline-dean-11322/.
  5. Twitter, Twitter, https://twitter.com/CarolineDeanLab.
  6. Genial.ly images

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