Thymus and bone marrow

and thymus

Lymphoid organs

Bone marrow

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Thymus

Thymocyte

Thymic epithelial cells

Hematopoiesis

lymphoid organ

Bone marrow

Glossary

They are considered primary or central organs, in these organs the lymphocytes originate and differentiate, through the mechanism of lymphopoiesis (every day around 10^9 lymphocytes are produced) and the acquisition of the morphological and molecular characteristics that enable them to respond before an antigen.

Bone marrow

Thymus

What type of lymphoid organs are they?

Two important functions shared by the generative organs are to provide growth factors and other molecular signals needed for lymphocyte maturation and to present self antigens for recognition and selection of maturing lymphocytes The bone marrow and the thymus are the sites of maturation of B cells and T cells, respectively.

Thymus

Bone marrow

¿Why is important this/these organs(s)? ¿What does It do?

Thymus

Structure of the thymus

Bone marrow structure

In the medulla, there are structures called Hassall corpuscles, which are composed of tightly packed whorls of epithelial cells that may be remnants of degenerating cells. The thymus has a rich vascular supply and efferent lymphatic vessels that drain into mediastinal lymph nodes. The epithelial component of the thymus is derived from invaginations of the ectoderm in the developing neck and chest of the embryo, forming structures called branchial pouches. DCs, macrophages, and lymphocyte precursors are derived from the bone marrow.

Refer two similarities and two differences with another lymphoid organs

Summary

Bibliography

"Abbas AK, Lichtman AH, Shiv Pillai. Cellular and molecular immunology. Philadelphia: Elsevier/Saunders, Cop; 2012.

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